Note: PDF files are for use by students for personal copies only

Mechanisms of adherence, invasion, and intracellular survival

6. Tuesday, February 3, 2004

Assigned article:

Justice SS, Hung C, Theriot JA, Fletcher DA, Anderson GG, Footer MJ, Hultgren SJ. 2004. Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis. Proc Natl Acad Sci U S A. 101:1333-1338. PDF (560 KB)

Related article:

Anderson GG, Palermo JJ, Schilling JD, Roth R, Heuser J, Hultgren SJ. 2003. Intracellular bacterial biofilm-like pods in urinary tract infections. Science 301:105-107. PDF (460 KB)

7. Thursday, February 5, 2004.

Assigned article:

Valle J, Toledo-Arana A, Berasain C, Ghigo JM, Amorena B, Penades JR, Lasa I. 2003. SarA and not sigmaB is essential for biofilm development by Staphylococcus aureus. Mol. Microbiol. 48:1075-1087. PDF (367 KB)

Useful Review:

Boyle, EC, Finlay BB. 2003. Bacterial pathogenesis: exploiting cellular adherence. Curr. Opin. Cell Biol. 15:633–639. PDF (710 KB)

8. Tuesday, February 10, 2004.

Assigned article:

Amieva MR, Vogelmann R, Covacci A, Tompkins LS, Nelson WJ, Falkow S. 2003. Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA. Science 300:1430-1434. PDF (787 KB)

9. Thursday, February 12, 2004.

Lilic M, Galkin VE, Orlova A, van Loock MS, Egelman EH, Stebbins CE. Salmonella SipA polymerizes actin by stapling filaments with nonglobular protein arms. Science. 301:1918-1921. PDF (386 KB)

Related article:

Gouin E, Egile C, Dehoux P, Villiers V, Adams J, Gertler F, Li R, Cossart P. 2004.

The RickA protein of Rickettsia conorii activates the Arp2/3 complex. Nature 427:457-461. PDF (336 KB)

Useful Review:

Gruenheid S, Finlay BB. 2003. Microbial pathogenesis and cytoskeletal function. Nature 422:775-781. PDF (1374 KB)

10. Tuesday, February 17, 2004.

Assigned article:

Mansfield BE, Dionne MS, Schneider DS, Freitag NE. 2003. Exploration of host-pathogen interactions using Listeria monocytogenes and Drosophila melanogaster. Cell. Microbiol. 5:901-911. PDF (533 KB)

Related article:

Cheng LW, Portnoy DA. 2003. Drosophila S2 cells: an alternative infection model for Listeria monocytogenes. Cell. Microbiol. 5:875-885. PDF (593 KB)

Useful Review:

O’Riordan M, Portnoy DA. 2002. The host cytosol: the frontline or home front? Trends Microbiol. 10:361-364. PDF (315 KB)

11. Thursday, February 19, 2004.

Assigned Article:

O'Riordan M, Moors MA, Portnoy DA. 2003. Listeria intracellular growth and virulence require host-derived lipoic acid. Science 302:462-464. PDF (157 KB)

Note: PDF files are for use by students for personal copies only

Toxins section (Drs. Blanke and Koehler)

Tues, Feb. 24

12. Thurs., Feb. 26