"Rule out everything"

Clinical history:
A 39-year-old woman was admitted to the pulmonary service with fever and productive cough. Chest x-ray showed bilateral diffuse infiltrates. History was notable for a renal transplant 8 months previously. A bronchoalveolar lavage was performed. Cytologic evaluation was requested to rule out infection due to fungi, Pneumocystis, acid-fast bacilli, cytomegalovirus and malignancy.

Pathology:
35 mls of BAL fluid was processed for routine cytospins which showed a mixed cellular population including macrophages, moderate numbers of neutrophils and scattered bronchial epithelial cells. Staining for acid-fast bacilli was negative. The Gomori methenamine silver (GMS) stain revealed the following at 400X magnification:



                             cytmys21.jpg (22702 bytes)





                                         Diagnosis?

                                           Solution