Gyncologic cytology
Cervicovaginal (Pap) smears, conventional
1. Within normal limits
Image 1 (normal endocervical cells)
Image 2 (endometrial stromal cells)
Image 3 (endometrial stromal cells)
2. Benign cellular changes (BCC), reactive/reparative change
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3. BCC, atrophy with inflammation
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4. BCC, radiation effect
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5. BCC, follicular cervicitis
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6. BCC, postpartum changes
Image 1
7. BCC, predominance of coccobacilli
Image 1
8. BCC, Trichomonas
Image 1
Image 2 (+leptothrix)
Image 3 (+leptothrix)
9. BCC, Candida
Image 1
Image 2
10. BCC, changes associated with herpesvirus infection
Image 1
11. BCC, hyperkeratosis
Image 1
12. Atypical squamous cells of undetermined significance (ASCUS)
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13. Low grade squamous intraepithelial lesion (LGSIL)
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14. High grade squamous intraepithelial lesion (HGSIL)
Image 1, cervical intraepithelial neoplasia (CIN) II
Image 2, CIN III
Image 3, CIN III
Image 4, CIN III
Image 5, CIN III
Image 6, CIN III (CIS)
Image 7, CIN III (CIS)
Image 8, CIN III (CIS)
Image 9, CIN III (CIS)
Image 10, CIN III (CIS)
Image 11, CIN III (CIS)
Image 12, CIN III (CIS)
Image 13, CIN III (CIS)
Image 14, CIN III (CIS)
Image 15, CIN III (CIS)
15. Invasive squamous cell carcinoma
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16. Atypical glandular cells of undetermined significance (AGUS)
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17. Adenocarcinoma (endometrial)
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Image 3 (+ histologic correlation)
Image 4 (+ histologic correlation)
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18. Adenocarcinoma in situ (endocervical)
Image 1 (+ histologic correlation)
Image 2 (+ histologic correlation)
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19. Adenocarcinoma (endocervical)
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20. Adenocarcinoma, NOS
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Image 8
21. Artifacts and limitations
Image 1 (BCC, interpretation limited by air drying artifact)
Image 2 (Unsatisfactory, scant cellularity)
Image 3 (Limited by smear thickness and inflammation)
Image 4 (LGSIL, limited by air-drying and inflammation)
Image 5 (WNL, limited by cytolysis)
Image 6 (HSIL, limited by obscuring inflammation)
Cervicovaginal (Pap) smears, ThinPrep
1. Within normal limits
Image 1 (pseudokoilocytosis)
Image 2 (atrophy)
Image 3 (atrophy
Image 4 (atrophy)
Image 5 (atrophy)
Image 6 (atrophy)
Image 7 (atrophy)
2. Benign cellular changes (BCC) associated with inflammation
Image 1
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3. BCC, reactive changes
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4. BCC associated with Candida
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5. BCC associated with herpesvirus infection
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Image 5
6. BCC, predominance of coccobacilli
Image 1
7. BCC, Trichomonas
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Image 7
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8. BCC, atrophy with inflammation
Image 1
Image 2
9. BCC, hyperkeratosis
Image 1
Image 2
10. Atypical squamous cells of undetermined significance (ASCUS)
Image 1
Image 2
Image 3
11. Low grade squamous intraepithelial lesion (LGSIL)
Image 1
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12. High grade squamous intraepithelial lesion (HGSIL)
Image 1, CIN III
Image 2 ,CIN II
Image 3, CIN II
Image 4, CIN II
Image 5, CIN II
Image 6, CIN II
Image 7, CIN III
Image 8, CIN II
Image 9, CIN III
Image 10, CIN III
Image 11, CIN III
II. Non-gynecologic cytology
Common bile duct, brushings
1. Adenocarcinoma, consistent with cholangiocarcinoma
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Lung, bronchoalveolar lavage and bronchial washings
1. BAL, negative for malignancy
Image 1
2. BAL, inclusions c/w CMV infection
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3. BAL/bronchial washings, ferruginous bodies
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4. Bronchial washings, oxalate crystals (polarized light)
Image 1
Lung, bronchial brushings
1. Normal bronchial epithelium
Image 1
2. Adenocarcinoma
Image 1
3. Small cell carcinoma
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4. Non-small cell carcinoma
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Image 3
Lung, fine needle aspiration
1. Adenoid basal carcinoma
Image 1
2. Poorly differentiated carcinoma, non-small cell
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3. Metastatic melanoma
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Liver, fine needle aspiration
1. Normal hepatocytes
Image 1
2. Hepatocellular carcinoma
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Image 3 (cell block)
Image 4 (biopsy)
Lymph node, fine needle aspiration
1. Metastatic signet ring cell adenocarcinoma
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2. Metastatic non-small cell carcinoma, lung primary
Image 1
3. Metastatic melanoma
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4. Metastatic ductal carcinoma, breast
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Lymph node, touch preps
1. Follicular lymphoma, predominantly small cleaved cell
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Image 3 (histology, same case)
Breast, fine needle aspiration
1. Fibroadenoma
Image 1
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Salivary gland, fine needle aspiration
1. Pleomorphic adenoma
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2. Warthin's tumor
Image 1
3. Adenoid cystic carcinoma
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Thyroid, fine needle aspiration
1. Nodular goiter
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2. Papillary carcinoma
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3. Hashimoto's thyroiditis
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Soft tissue, fine needle aspiration
1. Pelvic mass, B-cell lymphoma
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Body fluids
1. Mesothelioma (pleural fluid)
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Image 6 (pleural fluid, cell block)
Image 7 (pleural biopsy)
Image 8 (pleural biopsy, cytokeratin immunostain)
2. Adenocarcinoma (pleural fluid)
Image 1
Image 2 (breast origin)
Image 3 (breast origin)
3. Adenocarcinoma (peritoneal fluid)
Image 1 (gastric origin - signet ring cell adenoCA)
Image 2 (gastric)
Image 3 (gastric)
Image 4 (gastric)
4. Small cell carcinoma (pleural fluid)
Image 1
Image 2
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