CURRICULUM VITAE

 

DIANE L.M. HICKSON-BICK

 

Telephone: (281) 997-6602 (Home)

(713) 500 5328 (Office)

(713) 500 0730 (Fax),

email:Diane.L.Bick@uth.tmc.edu

 

 

BUSINESS MAILING ADDRESS: Dept of Pathology and Laboratory Medicine,

UT-Houston Medical School

6431 Fannin, P.O. Box 20708

Houston, Texas 77225

 

 

PERSONAL: Birthplace: Banbury, Oxfordshire, England

 

EDUCATION: B.Sc., Hon. 1975: Birmingham University (U.K.). Major:  Medical Biochemistry

 

 

Ph.D., 1993: Baylor College of Medicine. Major:  Molecular Physiology and Biophysics.

 

POSITIONS HELD:

Sept1996-Present: Assistant Professor, Department of Pathology and Laboratory Medicine, UTHSC at Houston.

 

May -Aug 1996: Senior Research Associate, Department of Pathology and Laboratory Medicine, UTHSC at Houston.

1989-1996: Senior Research Associate, Baylor College of Medicine, Houston, TX.,

 

1978-1988: Research Assistant, Baylor College of Medicine, Houston TX.

 

1975-1978: Instructor in Biochemistry, St. Thomas' Hospital Medical School,

London, England.

 

 

MEMBERSHIPS:
Biochemical Society;

American Association for the Advancement of Science;

International Society for Heart Research,

Fellowship in Arteriosclerosis; Thrombosis and Vascular Biology council, American Heart Association.

 

 

PUBLICATIONS:

 

  1. H.J. Pownall, Q. Pao, D. Hickson, J.T. Sparrow, S.K. Kusserow, and J.B. Massey. Kinetics and mechanism of association of human plasma apolipoproteins with dimyristoylphosphatidylcholine:  Effect of protein structure and lipid clusters on reaction rates. Biochemistry 20:6630-6635, 1981.

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  2. H.J. Pownall, D. Hickson, and A.M. Gotto, Jr. Thermodynamics of lipid-protein association:  The free energy of association of lecithin with reduced and carboxymethylated apolipoprotein A-II from human plasma high density lipoprotein. J. Biol. Chem. 256:9849-9854, 1981.

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  3. H.J. Pownall, Q. Pao, D.L. Hickson, J.T. Sparrow, and A.M. Gotto, Jr. Thermodynamics of lipid-protein association in human plasma lipoproteins. Biophys. J. 37:175-176, 1982.

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  4. H.J. Pownall, D. Hickson, A.M. Gotto, Jr., and J.B. Massey. Kinetics of spontaneous and plasma-stimulated sphingomyelin transfer. Biochim. Biophys.Acta 712:169-176, 1982.

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  5. H.J. Pownall, D.L. Hickson, and L.C. Smith. Transport of biological lipophiles:  Effect of lipophile structure. J. Amer. Chem. Soc. 105:2440-2445, 1983.

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  6. J.B. Massey, D.L. Hickson, H.S. She, J.T. Sparrow, D.P. Via, A.M. Gotto, Jr., and H.J. Pownall. Measurement and prediction of the rates of spontaneous transfer of phospholipids between plasma lipoproteins. Biochim. Biophys. Acta 794:274-280, 1984.

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  7. H.J. Pownall, D.L.M. Hickson, A.M. Gotto, Jr., and J.B. Massey. In vitro transfer of phosphatidylcholines and their ether analogs by a human and rat plasma exchange factor. Biochem. Biophys. Res. Commun. 119:452-457, 1984.

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  8. J.B. Massey, D.L.M. Hickson-Bick, D.P. Via, A.M. Gotto, Jr., and H.J. Pownall. Fluorescence assay of the specificity of human plasma and bovine liver phospholipid transfer proteins. Biochim. Biophys. Acta, 835:124-131, 1985.

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  9. D. Hickson-Bick, R.D. Knapp, J.T. Sparrow, D.A. Sparrow, A.M. Gotto, Jr., J.B. Massey, and H.J. Pownall. Kinetics and mechanism of transfer of synthetic model apolipoproteins. Biochemistry, 27:7881-7886, 1988.

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  10. J.B. Massey, D.L.M. Hickson-Bick, A.M. Gotto, Jr., and H.J. Pownall. Kinetics of tryptic hydrolysis as a probe of the structure of human plasma apolipoprotein A-II. Biochim. Biophys. Acta, 999:121-127, 1989.

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  11. H.J. Pownall, D. Hickson-Bick, and J.B. Massey. Effects of hydrophobicity on turnover of plasma high density lipoproteins labeled with phosphatidylcholine ethers in the rat. J. Lipid Res. 32, 793-800, 1991.

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  12. H.J. Pownall, D.L. Bick, and J.B. Massey. Spontaneous phospholipid transfer: Development of a quantitative model. Biochemistry 30, 5696-5700, 1991.

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  13. Taffet, T.T. Pham, D.L.M. Bick, M. L. Entman, H.J. Pownall, and R.J. Bick. The calcium uptake of the rat heart sarcoplasmic reticulum is altered by dietary lipid. J. Membrane Biol. 131, 45-42, 1993.

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  14. Pappolla, M.A., Sos, M., Bick, R.J., Hickson-Bick, D.L.M., Reiter, R.J., Efthimiopoulos, S., Robakis, N.K. ( In Press) Oxidative Damage and Death of Cells Exposed to the Alzheimer Amyloid Peptide is completely Prevented by Melatonin. International Meeting on Alzheimers Disease.

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  15. Pappolla, M.A., Sos, M., Bick, R.J., Hickson-Bick, D.L.M., Reiter, R.J., Efthimiopoulos, S., Robakis,N.K. (1997) Melatonin Prevents Death of Neuroblastoma Cells Exposed to the Alzheimer Amyloid Peptide. J of Neuroscience 17, 1683:1690.

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  16. Massey, J.B., Bick, D.H. and Pownall, H.J. (1997) Spontaneous Transfer of Monoacyl Amphiphiles between Lipid and Protein Surfaces. Biophysical J. 72, 1732-1743.

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  17. Pownall, H.J., Bick, D.H, Massey, J.B. (1997) Determination and Clinical Significance of Free Fatty Acids. Handbook of Lipoprotein Testing, ed Rifai, N., Warnick, R. and Dominiczak, H. (In Press).

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  18. H. J. Pownall and D. L. Bick. (1997) A Perspective on the Hypolipidemic Effects of N-3 Fatty Acids. Omega-3 Lipoproteins and Atherosclerosis. (J. Davignon, J. Ch. Fruchart, and J. M. Ordovas, Eds.). John Libbey Eurotext. Paris, p 207-212. 1996.