A. ISSUED:
United States Patent 4,963,236 issued October 16, 1990 entitled "Apparatus and Methods for the Isoelectric Focusing of Biological and Amphoteric Substances". L. Scott Rodkey and G. David Huff. This patent describes instrumentation for preparative scale isoelectric focusing of large quantities of biomolecules. Assigned to Ampholife Technologies, Inc., The Woodlands, Texas and the Board of Regents of the University of Texas System, Austin, Texas.
United States Patent 5,160,594 issued November 3, 1992 entitled "Apparatus and Methods for the Isoelectric Focusing of Amphoteric Substances Incorporating Ion Selective Membranes in Electrode Chambers". G. David Huff and L. Scott Rodkey. This patent is a Continuation-in-Part of patent 4,963,236 describing engineering design enhancements that eliminate ion movement from anolyte and catholyte chambers into the separation chambers. Assigned to Ampholife Technologies, Inc., The Woodlands, Texas, and Board of Regents of the University of Texas System, Austin, Texas.
United States Patent 5,173,160 issued December 22, 1992 entitled "Analysis of Carrier Ampholytes Using Immobilized pH Gradients". L. Scott Rodkey and Keith A. Knisley. This patent describes a method for ampholyte analysis that makes possible the precise determination of the distribution of carrier ampholyte molecules in a pH gradient. It makes possible a quality control method for ampholyte analysis that will assure reproducibility of pH gradients and allow direct comparisons of ampholytes from different manufacturers. Assigned to Board of Regents of the University of Texas System, Austin, Texas.
United States Patent 5,322,906 issued June 21, 1994 entitled "Synthesis of Complex Polyamines for Ampholyte Production". L. Scott Rodkey and Philip R. DeShong. This application describes chemical approaches for production of complex polyamine molecules that can be used for synthesizing high-resolution ampholytes. High-resolution ampholytes can be fractionated into extremely narrow pH gradients (<0.5 pH units) for use in high-resolution analysis or preparation of soluble biopolymers. Assigned to Board of Regents of the University of Texas System.
United States Patent 5,428,116 issued June 27, 1995 entitled "Synthesis of Complex Polyamines for Ampholyte Production". L. Scott Rodkey and Philip R. DeShong. This is a Divisional Application of patent 5,322,906. This patent describes additional chemistry applied to production of complex polyamine molecules that can also be used for synthesizing high-resolution ampholytes. Assigned to Board of Regents of the University of Texas System.
United States Patent 5,840,585 issued November 24, 1998 entitled "Rh Blood Group Antigen Compositions and Methods of Use". L. Scott Rodkey, Marwan A Yared and Kenneth J. Moise, Jr. Methodology is described for isolation of a soluble form of serologically active red cell Rh antigens and their use in solid phase immunoassays and immunoadsorbents. Assigned to Board of Regents of the University of Texas System, Austin, Texas, and Baylor College of Medicine Board of Regents, Houston, Texas.
United States Patent 6,191,108 issued February 20, 2001 entitled "Rh Blood Group Antigen Compositions and Methods of Use". L. Scott Rodkey, Marwan A. Yared, and Kenneth J. Moise, Jr. CIP of patent 5,840,585 containing specific claims for use of the Rh antigen extract in ELISA and related immunoassays. Assigned to the Board of Regents of the University of Texas System, Austin, Texas, and Baylor College of Medicine Board of Regents, Houston, Texas.
Swedish Patent 9302737-3 issued May 22, 2000 entitled "Analysis of Carrier Ampholytes Using Immobilized pH Gradients". This is identical to US Patent 5,173,160.
United States Patent 6,280,958 issued August 28, 2001 entitled "Rh Blood Group Antigen Compositions and Methods of Use". L. Scott Rodkey, Marwan A. Yared, and Kenneth J. Moise, Jr. CIP of patent 5,840,585 containing specific claims for Immunodetection of anti-RhD antibodies. Assigned to the Board of Regents of the University of Texas system, Austin, Texas, and Baylor College of Medicine Board of Regents, Houston, Texas.
United States Patent 6,551,830 issued April 22, 2003 entitled "Rh Blood Group Antigen Compositions and Methods of Use". L. Scott Rodkey, Marwan A. Yared, and Kenneth J. Moise, Jr. Specific claims cover methods for stabilizing and immobilizing the Rh antigen. Assigned to the Board of Regents of the University of Texas system, Austin, Texas, and Baylor College of Medicine Board of Regents, Houston, Texas.
B. Pending
One divisional and an international application of US patent 5,840,585 "Rh Blood Group Antigen Compositions and Methods of Use" have been filed.
Further information on these patents can be obtained from Dr. Rodkey at 713-500-5342 or at L.Scott.Rodkey@uth.tmc.edu
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